Laurence Anyways is a 2012 Canadian film that tells the story of impossible love between a man and a woman after the man decided to have a sex change, according to IMDB.
The film competed in the Un Certain Regard section at the 2012 Cannes Film Festival where Suzanne Clément won the Un Certain Regard Award for Best Actress. The film was also awarded with the Queer Palm Award at the festival, according to Wikipedia.
After watching the trailer, I want to see the film.
Thank you Accro for alerting me about it.