From about 1940 to 1970, Diethylstilbestrol (DES) was given to pregnant women in the mistaken belief it would reduce the risk of pregnancy complications and losses. - from Wikipedia
I was born in 1951.
Recent research on DES sons [males who were prenatally exposed to DES] has explored the hypothesis that the range of effects of prenatal exposure to DES in males might include behavioral or neurological change, and also intersexuality.
Dr. Scott Kerlin of the DES Sons International Research Network has documented for the past 15 years "the high prevalence of individuals with confirmed or strongly suspected prenatal DES exposure who self-identify as male-to-female transsexual, transgender, and intersexed, and many individuals who have reported experiencing difficulties with gender dysphoria.
Various neurological changes occur after prenatal exposure of embryonic males to DES and other estrogenic endocrine disrupters. Animals that exhibited these structural neurological changes were also shown to demonstrate various gender-related behavioral changes (so called "feminisation of males").
Several published studies in the medical literature on psycho-neuro-endocrinology have examined the hypothesis that prenatal exposure to estrogens (including DES) may cause significant developmental impact on sexual differentiation of the brain, and on subsequent behavioral and gender identity development in exposed males and females.There is significant evidence linking prenatal hormonal influences on gender identity and transsexual development. - from Wikipedia
I don't know if Mom ever took DES. My parents and Mom's doctor are deceased, so I can't ask them.
For your consideration: